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Dual modification

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Biochemical Assay Reagents

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145942
    Octenyl succinic anhydride

    		Biochemical Assay Reagents Inflammation/Immunology
    Octenyl succinic anhydride can be used to esterify Starch to yield a hydrocolloid with amphiphilic properties, octenyl succinylated starch (OS-starch). Octenyl succinic anhydride (OSA) modification affects interaction between molecules on the outer surfaces of two starch granules by altering molecular structures on the outer surfaces .
    Octenyl succinic anhydride
  • HY-163105
    Tubulin/NEDDylation-IN-1

    		Microtubule/Tubulin Cancer
    Tubulin/NEDDylation-IN-1 (compound C11) is a dual inhibitor of tubulin (Microtubule/Tubulin)-NEDDylation (IC50 for tubulin=2.40 μM), which has strong anti-proliferative activity. Neddylation is a protein post-translational modification that covalently tags the ubiquitin-like protein NEDD8 to target proteins. Tubulin/NEDDylation-IN-1 forms hydrogen bonds with residues of tubulin and E1 NEDD8 activating enzyme (NAE) through methoxy and dithiocarbamate groups and inhibits NEDDylation and microtubulin in an ATP-dependent manner. tube polymerization .
    Tubulin/NEDDylation-IN-1

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